You should wear your aligners 20-22 hours a day, only removing them to eat, drink, brush, and floss. You can expect to change to a new set of aligners every 1 to 2 weeks.
You can use the Invisalign Cleaning System to care for your aligners, or you can brush them with a toothbrush and toothpaste and rinse them with lukewarm water. Avoid using hot water because it can warp the plastic, ruining the aligner. Be sure to brush your teeth after every meal before you place your aligners back into your mouth.